17 May Rhinosporidiosis is a disease caused by the organism Rhinosporidium seeberi, which was once thought to be a fungus but is now believed to. 18 May Nasal cavity, paranasal sinuses, nasopharynx – Rhinosporidiosis. Rhinosporidiosis is a chronic infective disorder caused by Rhinosporidium seeberi. It usually presents as a soft polypoidal pedunculated or sessile mass.

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Rare sites of involvement are lips, palate, uvula, rhinossporidiosis antrum, epiglottis, larynx, trachea, bronchus, ear, scalp, vulva, penis, rectum and skin. Lymphadenitis, trans-epidermal elimination and unusual histopathology in human rhinosporiodiosis.

Phylogenetic analysis of Rhinosporidium seeberi’s 18S small-subunit ribosomal DNA groups this pathogen among members of the protoctistan Mesomycetozoa clade. Pathologic Features Gross Findings Rhinosporidiosis typically manifests as friable nasal polyps or masses, classically described as strawberry-like in appearance.

View large Download slide. Studies of the haematoxylin and eosin stain sections demonstrated the presence of globular cysts of varying sizes representing sporangia in different stages of development surrounded by a mixed inflammatory infiltrate comprising lymphocytes, eosinophils and neutrophils.

Background nonspecific chronic inflammation and edema, acute inflammation if cysts rupture. Abstract Rhinosporidiosis is a disease caused by Rhinosporidium seeberi which rhinosporidiosiz affects the mucosa of the nose, conjunctiva and urethra.

Cutaneous lesions are rare, even in India, Sri Lanka, and South America, where the causative agent, Rhinosporidium seeberiis endemic. The disease is endemic in wet tropical and subtropical environments, uncommon in North America and Africa, and rare in Europe. Dhinosporidiosis most common age group affected was years [ Table 1 ].

Clinicopathological study of rhinosporidiosis with special reference to cytodiagnosis

Moreover, it will be very crucial to follow in the next few years the clinical course of these patients to exclude the possibility of recurrence of the lesion, which usually occurs rhinodporidiosis an extended time period, to evaluate the best treatment for this infection.

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Similar experience has also been reported by other workers. Collapsing trachea or main-stem bronchus Trauma, stricture, foreign body, neoplasia Small airway disease Feline asthma Bronchitis Smoke inhalation Bronchopneumonia. Less outdoor activity and less chance of contact with animals could explain fewer incidences among women [ 14 ].

Rhinosporidiosis – Wikipedia

Through phylogenetic analysis of Rhinosporidium seeberi rhinosporidiosjs rRNA gene, this group of pathogens was originally identified by Ragan et al. By using this site, you agree to the Terms of Use and Privacy Policy. The rest of the clinical examination was within normal limits.

Clinically, rhinosporidiosis presents as polypoidal soft tissue mass, often pedunculated. Tyring, in Clinical Mycology Second EditionRhinosporidiosis Rhinosporidiosis is a chronic granulomatous disease caused by Rhinosporidium seeberi.

Functional endoscopic sinus surgery was performed. The diagnosis is made by biopsy with demonstration of thick-walled giant sporangia. Rhinosporidiosis is a chronic infestation by the fungus Rhinosporidium seeberiwhich predominantly affects the mucus membranes of the nose and nasopharynx.

Epistaxis and rhinorrhea are the common manifestations of nasal and nasopharyngeal infections. Since then, the microbe has been considered a fungus by most microbiologists, although its taxonomy has been debated.

Clinical Signs Richard B. As far as recurrence of the disease is concerned we presume that only our first case was a recurrent case as he gave a history which included two previous surgeries in a peripheral hospital in Bihar for the same condition.


The only curative approach is the surgical excision rhinospotidiosis with electrocoagulation. Rhinosporidiosis is a disease caused by Rhinosporidium seeberi which primarily affects the mucosa of the nose, conjunctiva and urethra. J Laryngol Otol ; The overwhelming majority of affected dogs are young-adult to middle-aged with a range of 1 to 13 years of ageotherwise-healthy, large-breed hunting dogs such as Labrador and golden retrievers, Doberman pinschers, Siberian huskies, German shepherds, and Rhodesian ridgebacks.

Cryptococcus neoformans Cryptococcosis Trichosporon spp Trichosporonosis. J Submicrosc Cytol Pathol ; Culture and serology are not currently available.

Rhinosporidiosis in Delhi, North India: The mass was excised in toto and the base was cauterized and sent for microbiological and histological ruinosporidiosis.

Cases have been reported worldwide, with an increased incidence in South America and Africa. Uncommon features noted in our cases were warty growth in the lips, palate and urethra, nasal infection with abscess formation, and anosmia.

Vilela R, Mendoza L. It is thus prudent for both clinicians and microbiologists to keep this condition in mind when managing patients with nasal masses even from non-endemic areas. The phylogenetic studies of Silva et al 86 also rhinosporidiosiis the presence of species-specific strains in the genus Rhinosporidiuma finding that could forecast the existence of novel host-specific species.

Isolated cases of dissemination involving deep organs have been rarely reported. It is now considered to be a protist [3] classified under Mesomycetozoea. All drugs were endospore-static rather than endosporicidal.

Detail of juvenile sporangia.